Query Name: 3717.m00027

Candidate fusion gene

Query Sequence:

MDLFKKIFQLQNDEESKSQTNKQGARHGQGMMHYNNGDKYEGEWYNNLRQGQGKQYYYNGDFYTGSWNKDKKEGHGQYFYSNNERYEGDWSNDLRHGKGKYFYRNGDIYDGSWVKGKKEGKGRMTYYNNEEYDGDWLNDKKHIKNSTQNNESKEENNHKRRKNGQEDNSNTNSYEEKNSIDQIRKVISNGSERKNSSPKNKKSIQDDKDYEYDYNKPSSNNIKEEIQNNLFSNNQINSNILESQQLQYTNQYHSNRDNDFAIATNVEESVSKSNIIATEVNDTYRTNGQSLQISIDDNKAIDILDIMESYEILNNFPQDLREWNTGHICKWLDSIGLGEFSPSFESNQICGQSICMLTEQELEQSIGMKALGKRKIFLKYQEMLKKYYNKKLSKDIKQFIHKHQSRFKKGEKSLQFLKQNQQNYRSIREEDESISSHKNSLNSNQINQMENFMLLEEDEDEDHSGGKKQKDKDKKNNSYRNSDDEQNKEKNENNKKNQKIKKKKRDKGSNNSSSNDESDYSQSDNQKVSGLRSRENSGSNLVNVKEDQKEKKQKRNSPQYQYINNNNNNFEENYKYKVELQKDKSKNFAGDEDEEIHKFLKFQKNKSQTEQQKHHNNHISKVQSDSTYNSHKLKIQQINNVYCEDKLFQDIKVEKKQNHKQSGDYAQNIQSESLLTEQNQELAYTISNGNYQNQDIQTAQDLNQNNIQEEEIKNQKQLSKEVNKTQSLDNSYVKKKKKDDKLGPRDGKFNNNSIESIDTLEQKQHKSDDAASVNQMNSPDIRQNDLIKSLQPDFINTKPFILNFNQSINQNENTLFKLGIQKDLFISDKNDSQKTGLTKITSSNQSGGQTLINQSSGAIGNPTAQNSSVENNSGQNKGMQISNNQLSSSSSSSDESSDNEPNKQVVNKRSKGDGGASISSQDSDTNSKLKQRQTPQQKFKKENTKDGSRNPSKDKATPQIKHKDKDKDKMKEVSKEKSRLRREEKQQQLDQLLRDMGINKKLIINYQELDFGKKIGEGSYGQVFKGTWAKTQVAIKQFGKQNSKFHLRKVQDFISEVRVINNLRHPNIVLYMGVCFYQSQYFMITEYLQEGSLYDHLHIKHTAFSEAKQIDMIEDMALGMVYLHGRKVMHCDLKSSNVLIDENWNVKLCDFGLSRIKSTLNKKKNARKNEGLIGTPQWMAPEIMRREQYQEHSDVYSFGMIMWEIATRKVPYLGLSHQQIYGTVGYDENYQVEIPVRGIPRYLNLMKKCLRRNPQERPTFQEVVEEIFKIKKDLKDNNKKIIRFFD

Significant Ortholog Group Hits and their Scores:

N terminus		C terminus
[T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase	49.9595153702233	[T] KOG4278 Protein tyrosine kinase	40
[R] KOG0231 Junctional membrane complex protein Junctophilin and related MORN repeat proteins	42.3205768944019	[T] KOG4721 Serine/threonine protein kinase, contains leucine zipper domain	40
		[T] KOG0574 STE20-like serine/threonine kinase MST	35.5555555555556
		[T] KOG0197 Tyrosine kinases	27.7777777777778
		[T] KOG0196 Tyrosine kinase, EPH (ephrin) receptor family	26
		[T] KOG0192 Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs	23.3707865168539
		[T] KOG0577 Serine/threonine protein kinase	20
		[T] KOG0193 Serine/threonine protein kinase RAF	20
		[T] KOG0579 Ste20-like serine/threonine protein kinase	20
		[T] KOG0201 Serine/threonine protein kinase	12.6315789473684
		[T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family	10
		[TU] KOG1026 Nerve growth factor receptor TRKA and related tyrosine kinases	10
		[R] KOG0597 Serine-threonine protein kinase FUSED	8
		[T] KOG0194 Protein tyrosine kinase	7.82608695652174
		[T] KOG0200 Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases	7.55555555555556
		[T] KOG0578 p21-activated serine/threonine protein kinase	7.27272727272727
		[T] KOG0198 MEKK and related serine/threonine protein kinases	6.77966101694915
		[T] KOG1025 Epidermal growth factor receptor EGFR and related tyrosine kinases	5.71428571428571
		[T] KOG1095 Protein tyrosine kinase	5.33333333333333

Graphs (click to enlarge):

BLAST of Query Sequence	Location of Ortholog Group Hits